Not known Facts About phenobarbital sodium injection dailymed
Not known Facts About phenobarbital sodium injection dailymed
Blog Article
pentobarbital will lessen the level or effect of buprenorphine buccal by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Keep an eye on.
There are no data on pregnancy exposures in primates similar to intervals previous to the 3rd trimester in humans.
pentobarbital will decrease the extent or effect of triazolam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Monitor.
Administer barbiturates with warning in patients with hepatic injury and at reduced doses to begin with; barbiturates should not be administered to individuals demonstrating the premonitory signs of hepatic coma
pentobarbital will reduce the level or effect of avanafil by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Observe. For patients with ED, keep track of response diligently due to likely for diminished effectiveness.
Physical exercise warning when administered to people with acute or chronic pain; could result in paradoxical exhilaration or vital symptoms can be masked
pentobarbital will decrease the level or effect of methadone by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Check.
Monitor Carefully (one)pentobarbital will lessen the level or effect of levamlodipine by influencing hepatic/intestinal enzyme CYP3A4 metabolism.
pentobarbital will lessen the extent or effect of nilotinib by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Use Caution/Watch.
pentobarbital will lessen the level or effect of apremilast by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Avoid or Use Alternate Drug. Coadministration with solid CYP inducers results in a big decrease of systemic exposure of apremilast, which may end in lack of efficacy
Inspection: Parenteral drug merchandise must be inspected visually for particulate issue and discoloration before administration, Any time solution containers permit. Solutions for injection demonstrating proof of precipitation shouldn't be used.
Keep track of Carefully (one)pentobarbital will reduce the extent or effect of fentanyl by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Check Carefully. Coadministration of fentanyl with CYP3A4 inducers could lead on to some lower in fentanyl plasma concentrations, not enough efficacy or, probably, progress of the withdrawal syndrome inside a client who may have developed physical dependence to fentanyl. Soon after halting a CYP3A4 read more inducer, given that the effects in the inducer decrease, the fentanyl plasma concentration will improve which could improve or lengthen both equally the therapeutic and adverse effects.
pentobarbital will minimize the level or effect of carvedilol by affecting hepatic enzyme CYP2C9/10 metabolism. Use Caution/Watch.
pentobarbital will reduce the level or effect of eucalyptus by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Insignificant/Importance Unknown.